| Development as a way of life: embedding cellular dynamics in physiological models | |
| Rod Smallwood Department of Computer Science University of Sheffield |
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| Authors | |
| Rod Smallwood | |
| Abstract | |
| The majority of mathematical and computational models of physiological processes in humans assume that there is a static population of cells within the tissues on the time scale of the process being modelled. It is assumed that the normal turnover of cells, and the changes in their organisation and function, take place on a timescale which is much longer than the process being studied. If we are interested in how we get from a normal to a diseased state, how tissues recover from insult, the changes that result from ageing or degenerative disease, then this assumption is not valid. The talk will discuss how cellular development can be incorporated into multiscale, multiparadigm physiological models. | |
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