Industry: Hottest General Area in recent corporate enterprise Intranet conference (after electronic commerce) was "application integration" -- linking the "ᡛ" separate major (SAP, PeopleSoft ..) applications (in typical large corporation) into a "grid"
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linking marketing, sales, production units with multiple databases and some computing
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(Industry) Engineering: There is classic multidisciplinary application in engineering design and manufacturing as in NASA's IPG (Information Power Grid) and ISE (Intelligent Synthesis Environment)
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DoD Metaproblems
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Image processing (target recognition) using Khoros
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Largest opportunity of this type in USA is perhaps SBA -- Simulation Based Acquisition -- SBA is plausibly built on top of DMSO HLA/RTI (CORBA like) commodity standards
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